PE-22-28 10mg

Description

Overview

PE-22-28 is a synthetic peptide fragment used as a molecular tool for investigating neuronal excitability, TREK-1 potassium channel function, and intracellular signaling pathways. In experimental research, it is applied to explore mechanisms such as cAMP accumulation, CREB phosphorylation, and neuroplasticity-associated responses. Its design ensures stability and reproducibility in both in-vitro and in-vivo preclinical models.

Researchers may buy PE-22-28 10 mg online to support precise mechanistic studies using research peptides.

Research Applications

PE-22-28 is utilized across neuroscience and ion-channel research in controlled laboratory settings, including:

• TREK-1 channel modulation:analysis of potassium conductance and ion-channel inhibition
• Neuronal signaling studies:monitoring cAMP levels, CREB phosphorylation, and downstream intracellular pathways
• Electrophysiology and imaging:assessment of neuronal firing, calcium flux, and membrane potential in cell cultures and rodent models
• Synaptic plasticity research:evaluation of neuronal proliferation, synapse formation, and transcription factor activation
• Neuroprotection and neuroplasticity pathways:preclinical modeling of cellular resilience and signaling mechanisms

Experimental design should consider concentration-dependent effects, matrix influences, and peptide stability under assay conditions.

Purchase & Use

PE-22-28 10 mg is available to order online as a research-use-only peptide for laboratories, academic institutions, and educational research facilities. Researchers can buy PE-22-28 10 mg online to support consistent and reproducible experimental studies with high-quality research peptides.

References

• Harmar AJ et al., Pharmacological Reviews, 2012
• Ohtaki H et al., Regulatory Peptides, 1998
• Waschek JA et al., Journal of Molecular Neuroscience, 1998