PTD-DBM
PTD-DBM 10 mg (Protein Transduction Domain–Dishevelled Binding Motif) is a specialized research peptide chemical designed for laboratory studies investigating cell signaling pathways associated with hair follicle biology. This peptide combines a PTD sequence, which may facilitate cellular entry, with a DBM sequence, which interacts with Dishevelled (Dvl) proteins involved in the Wnt/β-catenin signaling pathway. In experimental systems, PTD-DBM is explored for its potential to modulate the interaction between CXXC5 and Dvl proteins, providing researchers with a tool to study signaling dynamics related to cell proliferation and follicle function.
This product is strictly for research and educational use only. Not intended for human or veterinary consumption.
Description
Overview
PTD-DBM functions as a molecular probe in research settings, enabling scientists to study the Wnt/β-catenin pathway and its downstream effects on cellular growth, differentiation, and tissue maintenance. By influencing the interaction between CXXC5 and Dvl proteins, PTD-DBM is commonly employed in preclinical models to evaluate signaling mechanisms that regulate follicle stem cells, tissue regeneration, and growth-phase activation.
This peptide is suitable for in-vitro assays and select in-vivo experimental models, providing reproducible performance for mechanistic studies. Researchers can buy PTD-DBM online to support laboratory investigations requiring precise peptide chemistry and stability.
Research Applications
PTD-DBM is used in non-clinical laboratory research to explore multiple aspects of cellular and molecular signaling, including:
- Wnt/β-catenin signaling studies: probing pathway activation and regulatory feedback mechanisms
- Protein–protein interaction research: examining CXXC5–Dishevelled binding dynamics
- Follicle and stem cell investigations: studying molecular mechanisms underlying follicle growth, hair cycle regulation, and regenerative processes
- Cell proliferation and gene expression analysis: monitoring markers such as β-catenin, alkaline phosphatase (ALP), and PCNA in experimental models
- Combined pathway modulation studies: evaluating interactions with pathway activators or inhibitors to understand synergistic effects in controlled lab settings
These applications are intended solely for scientific exploration and educational research. PTD-DBM provides a versatile tool for researchers seeking insights into cell signaling networks without implying any therapeutic use.
Purchase & Use
PTD-DBM 10 mg is available to order online for qualified research institutions, laboratories, and academic programs. Researchers can buy PTD-DBM online to support reproducible, controlled studies in cellular signaling, molecular biology, and follicle research.
References (For Scientific Context)
- Lee SH et al., J Invest Dermatol, 2017;137(11):2260–2269
- NCBI PubChem Substance Record, SID 476298902, PTD-DBM Acetate
- Ryu YC et al., Br J Pharmacol, 2021;178(12):2533–2546
- Ryu YC et al., Experimental Hair Biology Studies
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