CJC-1295 (No DAC)
CJC-1295 (No DAC) is a laboratory-formulated research peptide chemical also known as Modified GRF (1–29). It is a synthetic analog of growth hormone–releasing hormone (GHRH) designed for experimental evaluation of receptor-mediated signaling along the growth hormone axis. In research settings, CJC-1295 (No DAC) is studied for its interaction with GHRH receptors and its role in short-acting endocrine signaling models.
Description
Overview
CJC-1295 (No DAC) is engineered without a Drug Affinity Complex, allowing investigators to examine transient receptor activation and signaling dynamics without extended peptide persistence. Within controlled laboratory environments, it is commonly applied to study GHRH receptor engagement, cAMP-linked intracellular pathways, and hypothalamic–pituitary signaling behavior.
Due to its defined structure and reproducible activity profile, CJC-1295 (No DAC) is frequently incorporated into research peptides workflows involving in-vitro assays and preclinical animal models. Researchers may buy CJC-1295 online to support mechanistic studies requiring precise temporal control of peptide signaling.
Research Applications
As a research-use-only chemical, CJC-1295 (No DAC) is utilized in non-clinical laboratory investigations such as:
- GHRH receptor pharmacology and ligand–receptor interaction studies
- Analysis of cAMP-dependent second-messenger signaling pathways
- Examination of pulsatile endocrine signaling in preclinical models
- Hypothalamic–pituitary axis pathway mapping in controlled experimental systems
- Comparative studies of short-acting versus extended-activity GHRH analogs
All applications are limited to experimental research settings and do not imply therapeutic or diagnostic use.
Peptide Design & Research Relevance
As a truncated GHRH analog, CJC-1295 (No DAC) is widely referenced in peptide chemistry research for evaluating how sequence modification influences receptor selectivity and signaling duration. The absence of DAC enables focused investigation of acute signaling responses, making it a useful research chemical for endocrine pathway studies.
Purchase & Use
CJC-1295 (No DAC) 5 mg is available to order online exclusively as a research-use-only peptide for qualified laboratories, academic institutions, and educational research facilities.
For Research Use Only (RUO). Not for human consumption.
References (For Scientific Context)
- Bowers CY et al., Endocrinology, 1990
- Teichman SL et al., Journal of Clinical Endocrinology & Metabolism, 2006
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