Nonapeptide-1
Nonapeptide-1 (Melanostatine-5) is a laboratory-grade research peptide chemical designed for experimental studies of pigment biology. This peptide modulates melanocortin-1 receptor (MC1R) signaling, influencing intracellular cAMP levels and tyrosinase activity in melanocyte cultures. It is commonly used in preclinical and in-vitro research to investigate pigment regulation, enzymatic pathways, and GPCR-mediated cellular signaling.
Description
Overview
Nonapeptide-1, also known as Melanostatine™ 5, is supplied exclusively for research and educational applications. Its synthetic structure ensures stability in laboratory experiments, making it a reliable tool for studying pigment-associated enzymatic activity and receptor–ligand interactions.
- Sequence (Three-Letter Code):Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val
- Molecular Formula:C61H87N15O9S
- Molecular Weight:52 g/mol
This research peptide is suitable for in-vitro cellular models, microbial systems, and selected preclinical research protocols.
Research Applications
Nonapeptide-1 10 mg is used in laboratory research to explore:
- Regulation of melanin synthesis and pigment-related cellular pathways
- Modulation of tyrosinase activity in cultured melanocytes
- α-MSH/MC1R receptor-mediated signaling mechanisms
- Controlled in-vitro and in-vivo experimental studies
- Broader peptide–receptor structure–function investigations
This peptide serves as a valuable tool for researchers conducting mechanistic studies in pigment biology and cellular signaling.
Purchase & Use
Nonapeptide-1 10 mg is available to buy online as a research-use-only chemical for laboratories, educational institutions, and academic research programs. Researchers can order Nonapeptide-1 online to support preclinical or educational experiments.
References
- Busca R et al., Pigment Cell Melanoma Research, 2007
- Park HY et al., Journal of Investigative Dermatology, 2009
- Loir B et al., European Journal of Dermatology, 2006
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