FOX-04-DRI 10mg
FOXO4-DRI (Proxofim) is a laboratory-formulated research peptide chemical engineered using a D-retro-inverso design strategy. This approach employs D-amino acids in a reversed sequence orientation to improve resistance to enzymatic degradation while maintaining functional interaction surfaces. In experimental models, FOXO4-DRI is used to study protein–protein interactions involving the FOXO4 transcription factor and cellular stress–response pathways.
Description
Overview
FOXO4-DRI is derived from a defined interaction region of the forkhead box O4 (FOXO4) protein and is commonly applied as a molecular research tool in laboratory environments. Its structural configuration allows researchers to explore FOXO4-associated signaling behavior, transcriptional regulation, and cellular fate determination under controlled experimental conditions.
In scientific literature, FOXO4-DRI is frequently referenced in studies examining how disruption of specific nuclear protein interactions influences senescent cell behavior. Due to its enhanced stability profile, it is well-suited for in-vitro assays and select in-vivo animal research models focused on cellular aging and stress signaling.
Researchers may buy FOXO4-DRI online to support mechanistic studies requiring consistent peptide performance and reproducibility.
Research Applications
As part of research peptides workflows, FOXO4-DRI is utilized in non-clinical laboratory investigations, including:
- Analysis of FOXO4-mediated transcriptional regulation in senescence-associated models
- Evaluation of protein–protein interaction dynamics, particularly within nuclear signaling environments
- Studies of p53-linked signaling pathways related to cellular stress and apoptosis thresholds
- Experimental modeling of cellular senescence, including oxidative stress– and toxicity-induced arrest systems
- Exploration of FOXO-regulated pathways associated with proteostasis, autophagy, and genomic stability
These applications are conducted strictly for exploratory and educational research purposes and do not imply therapeutic use.
Purchase & Use
FOXO4-DRI 10 mg is available to order online as a research-use-only chemical for qualified laboratories, academic institutions, and educational research facilities. Researchers looking to buy FOXO4-DRI online should review product specifications carefully to ensure compatibility with their experimental protocols.
References (For Scientific Context)
- Kirkland JL et al., Journal of Clinical Investigation, 2017
- Yosef R et al., Aging (Albany NY), 2017
- de Keizer PLJ, Trends in Molecular Medicine, 2017
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